Peptide-1 — now available

The shape
of reality.

Physical reality has structure. That structure can be learned. Once learned, it can be computed.

The Shape is building software that encodes the laws of physics, chemistry, biology, and beyond — and exposes them through a single API.

The Shape — math running on the substrate of reality

A new substrate

Reality is the substrate.
We compute on it.

The mission

We are building
a tiny pocket
of the universe.

For three centuries we wrote equations to describe reality. They were beautiful, and they were incomplete — solvable only for the simplest systems. Real molecules, real cells, real weather, real minds remained out of reach.

That ends now. The Shape is building foundation models that don't approximate reality — they compute it. Models that learn the underlying code of physics from data and run it forward. Peptide-1 is the first crack.

The endgame is the substrate that governs reality itself, in software. A tiny pocket of the universe — available through an API.

The Shape — math written on the substrate

The models

Reality, one scale at a time.

Every model is designed, trained, and served by The Shape. We start with biology — where physics becomes life — and expand outward.

Peptide-1

De novo peptide design & property prediction

Live

Peptide-1 generates and evaluates peptide sequences for binding affinity, stability, and therapeutic potential. Trained on curated protein-peptide interaction data.

View docs

One key. Every model.

Authenticate once. Send JSON. Get JSON back. The same pattern works for every model on The Shape — today and forever.

Low-latency inference on dedicated GPUs.
Your data is never used for training.
Pay per call. No subscriptions.

curl https://jointheshape.com/api/v1/models/peptide-1/predict \
  -H "Authorization: Bearer $SHAPE_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{
    "sequence": "MKWVTFISLLFLFSSAYS",
    "task": "predict_binding",
    "target": "GLP1R"
  }'

# => { "binding_affinity_kcal_mol": -8.7, "stability_score": 0.82, ... }

The shapeof reality.

Reality is the substrate.We compute on it.